| dc.contributor |
Fakultas Matematika dan Ilmu Pengetahuan Alam |
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| dc.creator |
Ramadhana, Arinda |
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| dc.creator |
Choesrina, Ratu |
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| dc.creator |
Yuniarni, Umi |
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| dc.date |
2019-08-09 |
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| dc.identifier |
http://karyailmiah.unisba.ac.id/index.php/farmasi/article/view/17637 |
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| dc.description |
Abstrak.Gastritis merupakan peradangan mukosa lambung. Pengobatan gastritis harus dilakukan secara tepat agar tidak menyebabkan komplikasi terhadap bagian tubuh lainnya. Dua atau lebih obat yang diberikan pada waktu bersamaan dapat menyebabkan perubahan farmakologis yang bersifat aditif, sinergis, dan antagonis. Penelitian ini bertujuan untuk menganalisis adanya potensi interaksi obat anti-gastritis pada peresepan, menentukan efek yang akan ditimbulkan, serta menentukan angka potensinya pada pasien Instalasi Rawat Inap di Salah Satu Rumah Sakit di Kota Tangerang. Penelitian ini merupakan jenis penelitian non-eksperimental dengan metode deskriptif dan teknik pengambilan data secara purposive sampling. Data yang diambil berupa data sekunder berbentuk data rekam medis responden. Sampel yang digunakan berjumlah 134. Hasil penelitian interaksi obat farmakokinetik yang terbanyak pada fase absorbsi adalah Ranitidin-Sukralfat sebanyak 9 (4.21%),dan pada fase metabolisme adalah Omeprazole-Simvastatin, Omeprazole-Atorvastatin masing-masing sebanyak 2 (0.93%). Interaksi obat farmakodinamik terbanyak yaitu Omeprazole-Sukralfat sebanyak 71 (33.18%). Interaksi obat berdasarkan tingkat keparahan minor terbanyak adalah Omeprazole-Ranitidin sebanyak 10 (4.83%), dan tingkat keparahan moderate terbanyak adalah Omeprazole-Sukralfat sebanyak 71 (34.30%).Keywords: Gastritis, antigastritis drugs, gastritis drug interactions Abstract. Gastritis is an inflammation of the gastric mucosa. Gastritis should be treated appropriately to prevent complications to the other body parts. Two or more medications administered at the same time can cause pharmacological effect changes that are additive, synergistic, and antagonistic. This research aims to analyze the interactions potential of prescribed anti-gastritis drugs, determine the effects that will be inflicted, and determine their potential figures toward inpatient treated in one of the hospitals in Tangerang city. The research was non-experimental with descriptive methods and purposive sampling data retrieval techniques. Data taken was in the form of secondary data from the medical record of respondents. 134 data samples were retrieved. The results showed that the most pharmacokinetic drug interactions in the absorption phase are Ranitidine-Sucralfate with 9 results (4.21%), in the metabolic phase are Omeprazole-Simvastatin and Omeprazole-Atorvastatin each with 2 results (0.93%). And the most pharmacodynamics of drug interactions are Omeprazole-Sucralfate with 71 results (33.18%). Drug interactions based on the most minor severity are the Omeprazole-Ranitidine with 10 results (4.83%), and the most moderate severity are Omeprazole-Sucralfate with 71 results (34.30%).Kata Kunci : Gastritis, obat antigastritis, interaksi obat gastritis |
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| dc.format |
application/pdf |
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| dc.language |
eng |
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| dc.publisher |
Universitas Islam Bandung |
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| dc.relation |
http://karyailmiah.unisba.ac.id/index.php/farmasi/article/view/17637/pdf |
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| dc.rights |
Copyright (c) 2019 Prosiding Farmasi |
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| dc.source |
Prosiding Farmasi; Vol 5, No 2, Prosiding Farmasi (Agustus, 2019); 481-488 |
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| dc.source |
Prosiding Farmasi; Vol 5, No 2, Prosiding Farmasi (Agustus, 2019); 481-488 |
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| dc.source |
2460-6472 |
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| dc.subject |
Farmasi |
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| dc.subject |
Gastritis, antigastritis drugs, gastritis drug interactions |
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| dc.title |
Analisis Potensi Interaksi Obat pada Resep Antigastritis di Salah Satu Rumah Sakit di Kota Tangerang |
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| dc.type |
info:eu-repo/semantics/article |
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| dc.type |
info:eu-repo/semantics/publishedVersion |
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| dc.type |
Peer-reviewed Article |
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| dc.type |
Kuantitatif |
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