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The Effect of Robusta Coffee Bean on Improving Sperm Quality On Mice Of Infertil Model

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dc.contributor
dc.contributor
dc.creator Wulandari, Mustika
dc.creator Soeherman2, R.B
dc.creator Furqanni, Annisa Rahmah
dc.date 2017-08-10
dc.date.accessioned 2019-09-13T05:58:45Z
dc.date.available 2019-09-13T05:58:45Z
dc.identifier http://karyailmiah.unisba.ac.id/index.php/dokter/article/view/8338
dc.identifier.uri http://hdl.handle.net/123456789/26363
dc.description The incidence of infertility is not stable but the incidence of infertility has increased sharply over the last few decades. It is estimated there are about 48.5 million couples in the world who can not have children after five years. Infertility can be caused by factors from men, as well as women. Male factors alone account for about 25% to 40%. Some of the causes that can cause infertility in men include the following: congenital abnormalities, infections, drugs, previous surgery, scrotal temperature, radiation, smoking history etc. This research was conducted by laboratory experimental method from March to May in Histology Lab Faculty of Medicine Padjadjaran University, with the aim to know the effect of robusta coffee on improving sperm quality in infertile mice. The samples were 34 male mice: 6 tails as normal control (K), 4 were given garlic infusions 75mg / head / day (B), 6 tails as infertile control (P0); 6 tails were given robusta coffee seed bean 72mg / kgBB (P1); 6 tails were given robusta coffee bean 36mg/ kgBB (P2); 6 tails were given 18mg / kgBW (P3). The results showed that there was an increase in the speed of sperm, especially with a dose of 72mg / kgBW; Increase in normal morphology of sperm especially at dose of 72mg / kgBB; There was no significant change in sperm count.
dc.description Angka kejadian infertilitas tidak stabil akan tetapi angka kejadian infertilitas meningkat secara tajam selama beberapa dekade terakhir ini. Diperkirakan ada sekitar 48,5 juta pasangan di dunia yang tidak dapat memiliki anak setelah lima tahun. Infertilitas dapat disebabkan karena faktor dari pria, dan juga wanita. Faktor pria sendiri menyumbang sekitar 25% sampai 40%. Beberapa penyebab yang dapat menyebabkan infertilitas pada pria diantaranya sebagai berikut: kelainan bawaan, infeksi, obat-obatan, operasi sebelumnya, temperature skrotum, radiasi, riwayat merokok dll. Penelitian ini dilakukan dengan metode eksperimental laboratoris dari bulan Maret sampai dengan Mei di Lab Histologi Fakultas Kedokteran Universitas Padjadjaran, dengan tujuan untuk mengetahui efek pemberian infusa biji kopi robusta terhadap peningkatan kualitas sperma pada mencit model infertil. Sampel sebanyak 34 ekor mencit jantan: 6 ekor sebagai kontrol normal (K), 4 ekor diberikan infusa bawang putih 75mg/ekor/hari (B), 6 ekor sebagai kontrol infertil (P0); 6 ekor diberi infusa biji kopi robusta 72mg/kgBB (P1); 6 ekor diberi infusa biji kopi robusta 36mg/kgBB (P2); 6 ekor diberikan 18mg/kgBB (P3). Hasil penelitian memperlihatkan ada peningkatan kecepatan pada pemberian infusa biji kopi robusta terutama dengan dosis 72mg/kgBB; peningkatan pada morfologi normal sperma terutama pada dosis 72mg/kgBB; tidak terdapat perubahan yang signifikan terhadap jumlah sperma.
dc.format application/pdf
dc.language ind
dc.publisher Universitas Islam Bandung
dc.relation http://karyailmiah.unisba.ac.id/index.php/dokter/article/view/8338/pdf
dc.rights Copyright (c) 2017 Prosiding Pendidikan Dokter
dc.source Prosiding Pendidikan Dokter; Vol 3, No 1, Prosiding Pendidikan Dokter (Agustus, 2017); 709-714
dc.source Prosiding Pendidikan Dokter; Vol 3, No 1, Prosiding Pendidikan Dokter (Agustus, 2017); 709-714
dc.source 2460-657X
dc.subject Medical Study
dc.subject infertile, robusta coffee, sperm quality
dc.subject Kedokteran
dc.subject Infertil, kopi robusta, kualitas sperma
dc.title The Effect of Robusta Coffee Bean on Improving Sperm Quality On Mice Of Infertil Model
dc.title Efek Pemberian Infusa Biji Kopi Robusta Terhadap Peningkatan Kualitas Sperma Pada Mencit Model Infertil
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion
dc.type Peer-reviewed Article
dc.type Quantitative
dc.type kuantitatif


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